Klaipėda is considered the most important Baltic Sea port, as it is ice-free almost all year round. The Baltic region with the three EU states of Lithuania, Latvia and Estonia has been developing for some time from an insider tip to a popular vacation region in Northern Europe. Lithuania's capital Vilnius and Latvia's capital Riga can be reached from Klaipėda in just under two hours by car.

The port of Karlshamn in the southeastern province of Blekinge is one of the largest ports in Sweden. From Karlshamn, a connection is offered to and from Klaipėda. The route between Trelleborg and Klaipėda remains, so Karlshamn - Klaipėda is offered in addition to Trelleborg - Klaipėda.